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Amyloid-related imaging abnormalities

Detect, measure and grade ARIA-E and ARIA-H

icobrain aria

icobrain aria can be used to assess side effects to amyloid-targeting therapies for Alzheimer's disease, known as amyloid-related imaging abnormalities (ARIA). It detects parenchymal vasogenic edema, gyral swelling and sulcal effusion.

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Dirk Smeets (CTO of icometrix) on icobrain dm and aria

Image by Lino C.

icobrain aria was thoroughly evaluated in large reader studies. It was demonstrated that the assistance of AI significantly improved radiologists’ ability to detect and classify ARIA, boosting both diagnostic sensitivity and accuracy, and adding a critical safety option for patients undergoing amyloid-targeting therapies

icobrain aria was thoroughly evaluated in large reader studies. It was demonstrated that the assistance of AI significantly improved radiologists’ ability to detect and classify ARIA, boosting both diagnostic sensitivity and accuracy, and adding a critical safety option for patients undergoing amyloid-targeting therapies

Jeffrey Cummings, Neurologist at University of Nevada

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87%

Sensitivity for ARIA-E detection
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79%

Sensitivity for ARIA-H detection
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>80%

Specificity for detection of both
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Image by Lino C.

I am excited that icobrain aria has received FDA approval, clearing the way for wider use in clinical practice. New standardized tools are needed, such as icobrain aria, to assist radiologists and treating clinicians in detecting and managing ARIA to optimize patient safety.

I am excited that icobrain aria has received FDA approval, clearing the way for wider use in clinical practice. New standardized tools are needed, such as icobrain aria, to assist radiologists and treating clinicians in detecting and managing ARIA to optimize patient safety.

Stephen Salloway, Neurologist at Brown University

Key scientific publications

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Latest news & press

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A Shared Language for ARIA: Standardizing Alzheimer’s Imaging in the Age of New Therapies with RSNA

With the arrival of disease-modifying therapies for Alzheimer’s disease, we are entering a new era in neurodegenerative care. But with...

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American College of Radiology (ACR) and icometrix collaborate to improve the quality of care for people with Alzheimer’s disease

Virginia, VA – April 2nd, 2025 The American College of Radiology (ACR), the professional medical society dedicated to advancing radiology...

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Market approval for icobrain aria

icometrix is proud to announce the market approval of icobrain aria , the first market-approved solution for monitoring amyloid-related...

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