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Amyloid-related imaging abnormalities
Detect, measure and grade ARIA-E and ARIA-H
icobrain aria
icobrain aria can be used to assess side effects to amyloid-targeting therapies for Alzheimer's disease, known as amyloid-related imaging abnormalities (ARIA). It detects parenchymal vasogenic edema, gyral swelling and sulcal effusion.
icobrain aria was thoroughly evaluated in large reader studies. It was demonstrated that the assistance of AI significantly improved radiologists’ ability to detect and classify ARIA, boosting both diagnostic sensitivity and accuracy, and adding a critical safety option for patients undergoing amyloid-targeting therapies
icobrain aria was thoroughly evaluated in large reader studies. It was demonstrated that the assistance of AI significantly improved radiologists’ ability to detect and classify ARIA, boosting both diagnostic sensitivity and accuracy, and adding a critical safety option for patients undergoing amyloid-targeting therapies
Jeffrey Cummings, Neurologist at University of Nevada
87%
Sensitivity for ARIA-E detection
79%
Sensitivity for ARIA-H detection
>80%
Specificity for detection of both
I am excited that icobrain aria has received FDA approval, clearing the way for wider use in clinical practice. New standardized tools are needed, such as icobrain aria, to assist radiologists and treating clinicians in detecting and managing ARIA to optimize patient safety.
I am excited that icobrain aria has received FDA approval, clearing the way for wider use in clinical practice. New standardized tools are needed, such as icobrain aria, to assist radiologists and treating clinicians in detecting and managing ARIA to optimize patient safety.
Stephen Salloway, Neurologist at Brown University
Key scientific publications
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